Gene therapy begins.

Endovascular Therapy: The Second Round Begins

Recently, randomized controlled trials have consistently confirmed the benefit of endovascular therapy in patients with acute large intracranial artery occlusion up to 6 hours. With these results, major stroke guidelines recommend endovascular recanalization therapy as standard stroke care. Now that we are moving towards expansion of the therapeutic time window, better patient selection, expedi...

A new era of hepatitis C therapy begins.

A new era of therapy for hepatitis C virus (HCV) infection is dawning with the development of two effective HCV protease inhibitors, boceprevir and telaprevir. In this issue of the Journal, the results of two phase 3 trials involving boceprevir, in combination with peginterferon and ribavirin, are presented: the SPRINT-2 (Serine Protease Inhibitor Therapy 2) trial (ClinicalTrials.gov number, NC...

ژن درمانی Gene Therapy

Tough climate roadmap begins

It was undoubtedly one of the most complex and global conferences: the meeting last month in Bali to tackle greenhouse gas emissions lived up to its billing with moments of high drama. Representatives of 190 countries had gathered to map out future plans to tackle global warming, with the US delegation finally agreeing to join in the process at the thirteenth hour (see Hard bargaining, this iss...

Equity begins with children

measure of income poverty and the more directly observable – and more reliable – indicators of human well-being. The former frequently yields a distorted view of reality. After examining the role of social services in human development, Anand and Ravallion (1993) conclude ‘that certain components of public